Isotopically Labeled Compounds
Medchemexpress LLC Methyl paraben-d4 | 362049-51-2 | 156.17 | 25 MG
Methyl paraben-d4 is the deuterium labeled Methyl Paraben. Methyl Paraben, isolated from the barks of Tsuga dumosa, the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. It is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release and cell-mediated immunity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Tyrosine-d2-2 | 57746-15-3 | 183.20 | 5 MG
L-Tyrosine-d2-2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC L-Lysine-d8 (hydrochloride) | 344298-93-7 | 190.70 | 1 MG
L-Lysine-d8 (hydrochloride) is the deuterium labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. It can also be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled L-Lysine hydrochloride.
- Essential amino acid for humans.
- Potential benefits include treating herpes, increasing calcium absorption, reducing diabetes-related illnesses, and improving gut health.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC p-Coumaric acid-d6 | 2708298-33-1 | 170.19 | 5 MG
p-Coumaric acid-d6 is a deuterium-labeled variant of p-Coumaric acid, which is a prominent isomer of cinnamic acid. This compound is recognized for its antitumor and anti-mutagenic properties. The deuterium labeling makes it useful in various scientific applications.
- Deuterium labeled.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Olaquindox-d4 | 1189487-82-8 | MFCD00210341 | 267.27 | 2.5 MG
Olaquindox-d4 | 1189487-82-8 | MFCD00210341 | 267.27 | 2.5 MG
Medchemexpress LLC D-Mannitol-13C | 132202-29-0 | 183.16 | 100 MG
D-Mannitol-13C is the 13C labeled version of D-Mannitol (HY-N0378). D-Mannitol is an oral, resistant sugar widely used in the food and pharmaceutical industries. It promotes the absorption and retention of calcium and magnesium through cecal fermentation and acts as an osmotic diuretic to reduce tissue edema. D-Mannitol can also enhance brown fat formation, improve insulin effect, and reduce blood sugar levels by activating the β3-adrenergic receptor (β3-AR), PGC1α, and PKA, which induces the conversion of white fat cells into brown fat cells. Additionally, D-Mannitol is commonly employed to maintain osmotic pressure between plant cytoplasm and the culture medium, and to protect cells when the cell wall is weakened or removed.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC L-Lysine-13C6,15N2 hydrochloride | 1200447-00-2 | 190.59 | 1 MG
L-Lysine-13C6,15N2 (hydrochloride) is the 13C- and 15N-labeled form of L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits, including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses, and improving gut health. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules as tracers for quantitation.
- Deuteration has gained attention due to its potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Leucine-d10 | 106972-44-5 | 141.23 | 50 MG
L-Leucine-d10 is a deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA) that activates the mTOR signaling pathway. Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs. This compound is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Activates the mTOR signaling pathway.
- Deuterium labeling can impact pharmacokinetic and metabolic profiles.
Medchemexpress LLC Thiamphenicol-d3-1 | 1217723-41-5 | 99.0% | 1 MG
Thiamphenicol-d3-1 is a deuterium-labeled form of Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol. It acts as a broad-spectrum antimicrobial antibiotic by binding to the 50S ribosomal subunit, inhibiting protein synthesis and resulting in a bacteriostatic effect against Gram-negative, Gram-positive aerobic, and anaerobic bacteria. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs, and stable heavy isotopes are incorporated for quantitation during drug development.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Exhibits broad-spectrum antimicrobial activity
- Inhibits protein synthesis by binding to the 50S ribosomal subunit
- Effective against Gram-negative, Gram-positive aerobic, and anaerobic bacteria
Medchemexpress LLC Spironolactone-d3 | 52-01-7 | 99.82% | 1 MG
Spironolactone-d3 is the deuterium labeled Spironolactone, an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. It also acts as a potent antagonist of androgen receptor with an IC50 of 77 nM and promotes autophagy in podocytes.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Vardenafil-d5 hydrochloride | 1189685-70-8 | 98.65% | 50 MG
Vardenafil-d5 hydrochloride | 1189685-70-8 | 98.65% | 50 MG
Medchemexpress LLC Azelaic acid-d14 | 119176-67-9 | 99.9% | 50 MG
Azelaic acid-d14 is the deuterium labeled Azelaic acid, an organic compound produced by the ozonolysis of oleic acid and a component of various hair and skin conditioners. It is intended for research use only.
- Used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeling may impact pharmacokinetic and metabolic profiles of drugs.
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development.
Medchemexpress LLC Urapidil-d3 | 1398066-08-4 | 99.9% | 1 MG
Urapidil-d3 | 1398066-08-4 | 99.9% | 1 MG